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The association between body mass index and efficacy and safety endpoints. The solid lines represent the incidence ratio (per 100 person-years) at each body mass index interval. The dashed lines represent the upper and lower bounds of the 95% confidence interval. The bars represent the distribution of body mass index values. The P values are for unadjusted trends.

Body Mass Index, Intensive Blood Pressure Management, and Cardiovascular Events in the SPRINT Trial

It is unclear whether intensive blood pressure management is well-tolerated and affects risk uniformly across the body mass index (BMI) spectrum. Methods The randomized, controlled Systolic Blood Pressure Intervention Trial (SPRINT) included 9361 individuals ≥50 years of age at high cardiovascular risk, without diabetes mellitus, with systolic blood pressure between 130 and 180 mmHg. Participants […]

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measuring belly fat with calipers

Impact of Body Mass Index and Genetics on Warfarin Major Bleeding Outcomes in a Community Setting

Several studies have demonstrated an association between body mass index (BMI) and warfarin therapeutic dose, but none evaluated the association of BMI with the clinically important outcome of major bleeding in a community setting. To address this evidence gap, we conducted a case–control study to evaluate the association between BMI and major bleeding risk among […]

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Sagittal abdominal diameter

Beyond Body Mass Index: Advantages of Abdominal Measurements

Sagittal abdominal diameter/height ratio and waist circumference/height ratio are better predictors of cardiometabolic disorders than body mass index. Background The clinical recognition of cardiometabolic disorders might be enhanced by anthropometry based on the sagittal abdominal diameter (SAD; also called “abdominal height”) or waist circumference rather than on weight. Direct comparisons of body mass index (BMI, […]

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tape measure

CME: Advances in the Management of Obesity

The American Journal of Medicine is offering a new continuing medical education course: Advances in the Management of Patients with Obesity. The course is based upon highlights from the 2013 Obesity Society Annual Meeting. Program Overview ObesityWeek 2013 was held on November 11–16, in Atlanta, GA and presented important data for the successful management of […]

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Surviving Bariatric Surgery

An Uncommon Option for Surviving Bariatric Surgery: Regaining Weight! In November 2011, a 32-year-old woman was admitted to the intensive care unit for acute respiratory failure. She had felt well consistently until February (including 2 pregnancies), when she underwent a noncomplicated sleeve gastrectomy for obesity (body mass index, 47 kg/m2). Her weight gain, unrelated to […]

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bmi-mortality.lrg

BMI & Mortality in Heart Attack Patients

Body Mass Index and Mortality in Acute Myocardial Infarction Patients The prevalence of obesity in the US has increased substantially in the past few decades. Current estimates place two thirds of adults in the US in the category of overweight or obese as defined by body mass index (BMI). In the general population, obesity is […]

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