American Journal of Medicine, internal medicine, medicine, health, healthy lifestyles, cancer, heart disease, drugs

Personalized Activity Intelligence (PAI) for Prevention of Cardiovascular Disease

To derive and validate a single metric of activity tracking that associates with lower risk of cardiovascular disease mortality. Methods We derived an algorithm, Personalized Activity Intelligence (PAI), using the HUNT Fitness Study (n = 4631), and validated it in the general HUNT population (n = 39,298) aged 20-74 years. The PAI was divided into three sex-specific […]

Read more

The Clinical Course of Venous Thromboembolism May Differ According to Cancer Site

We hypothesized that the clinical course of venous thromboembolism in patients with active cancer may differ according to the specificities of primary tumor site. Aim and Methods We used data from RIETE (international registry of patients with venous thromboembolism) to compare the clinical venous thromboembolism-related outcomes during the course of anticoagulation in patients with one […]

Read more

Restoring Balance: Paraneoplastic Cerebellar Degeneration

A 63-year-old woman was evaluated for 3 months of gradually worsening tremors in her legs. The tremors were worse in the right leg, increased in amplitude on standing or walking, and were absent at rest. She also had a milder tremor of her head. She had no headache, confusion, weakness, numbness, or dyscoordination. Her medical […]

Read more

Blood in Urine: A Hard Nut to Crack

A 34-year-old woman presented with a 2-week history of intermittent painless macroscopic hematuria. She had a similar episode of macroscopic hematuria 5 years ago during her last pregnancy, which resolved spontaneously. Apart from this, she had no significant medical history. She was not taking any regular medications or supplements. On examination, she appeared well. She […]

Read more

The Wrong Toothpaste and the Painful Burp

  Recurrent aphthous stomatitis is usually confined to the buccal mucosa, lips, and tongue. Rarely, the uvula may be involved. Although the disease is considered idiopathic, recurrences may be associated with the use of sodium lauryl sulfate-containing oral hygiene products. Objective To report a case of an aphthous ulcer located on the uvula, with an […]

Read more

Cardiovascular Risks of Exogenous Testosterone Use Among Men

We sought to evaluate whether exogenous testosterone therapy is associated with increased risk of serious cardiovascular events as compared with other treatments or placebo. Methods Study selection included randomized controlled trials (RCTs) and observational studies that enrolled men aged 18 years or older receiving exogenous testosterone for 3 or more days. The primary outcomes were […]

Read more

Bataclan’s Ulnar Nerve Syndrome

On November 13, 2015, during terrorist attacks in the Bataclan concert room (Paris, France), a 24-year-old man with no medical past history (except for thrombocytopenic purpura in childhood) was injured by gunshots on the left elbow. After having escaped, he was taken in charge by prehospital units and transferred to the emergency department of a […]

Read more
doctor uses tablet with patient

‘Urinary Tract Infection’ and the Microbiome

The current paradigm for managing uncomplicated “urinary tract infection” (“UTI”) is deeply flawed. “UTI” is ambiguously defined, and coupled with a belief that “bacteria are not normal inhabitants of the urinary tract,”1 the diagnosis often leads to unnecessary, harmful antibiotic treatment. Although bacteriuria identified by standard clinical cultures (which we will call standard bacteriuria) is central […]

Read more

The Missing Antibody: The Pitfalls of ANCA Testing

A 44-year-old white woman presented to the hospital with acute shortness of breath while on a flight back to England from a holiday in Turkey. She denied having a productive cough, hemoptysis, or chest or calf pain. She was asthmatic, and her symptoms were improved by repeated administration of her salbutamol inhaler during the flight. […]

Read more

Trends and Disparities in Osteoporosis Screening Among Women in the United States, 2008-2014

The United States Preventive Services Task Force recommends universal osteoporosis screening among women ages 65+ and targeted screening of younger women, but historically, adherence to these evidence-based recommendations has been suboptimal. Methods To describe contemporary patterns of osteoporosis screening, we conducted a retrospective analysis using the OptumLabs™ Data Warehouse, a database of de-identified administrative claims, which […]

Read more
UA-42320404-1