American Journal of Medicine, internal medicine, medicine, health, healthy lifestyles, cancer, heart disease, drugs

Moderate Alcohol Consumption Is Not Associated with Reduced All-cause Mortality

Although research suggests that moderate alcohol consumption is associated with reduced all-cause mortality, concerns remain that the observed relationship may be due to residual confounding. A large body of research suggests that light or moderate alcohol consumption is associated with reduced all-cause mortality. However, concerns remain that the observed relationship is due to selection bias, […]

Read more

Caught on Capsule: Iron-deficiency Anemia Due to Hookworm Infection (video)

A tiny ingestible camera identified an otherwise elusive source of anemia in a 63-year-old man. The patient presented to an outside hospital with a 2-week history of generalized weakness, malaise, nausea, and loss of appetite. He denied rectal bleeding. His past medical history was significant for a Billroth II gastric bypass and prior gastric angioectasias. […]

Read more

Top 10 Facts to Know About Inpatient Glycemic Control

Optimizing glycemic control should be a priority for all health care providers in the inpatient setting. Uncontrolled hyperglycemia in hospitalized patients with or without a previous diagnosis of diabetes is associated with adverse outcomes and longer lengths of hospital stay. It is estimated that one-third of hospitalized patients will experience significant hyperglycemia, and the cost […]

Read more

Retail Clinics: A Shift From Episodic Acute Care to Partners in Coordinated Care

The first retail clinic, offering care for common acute medical conditions, opened in a grocery store in Minneapolis in 2000.1 By 2015 there were 1900 retail clinics in the United States.2 Some have estimated that there will be 3000 retail clinics located in drug stores, grocery stores, and “big box” businesses in 2016.3 The majority are operated […]

Read more
Joseph S. Alpert

A Home Diagnosis

One of the things I like best about my work in clinical medicine is the occasional complete surprise that results from an unexpected diagnosis or response to therapy. Recently, I had what has to be the most remarkable and happy surprise during my long career in clinical medicine. It involved a woman of 83 years […]

Read more
white, male doctor smiling

Author Self-disclosure Compared with Pharmaceutical Company Reporting of Physician Payments

Caution is advised in the interpretation of Sunshine Act data and accuracy of guideline authors’ relationships with industry. Background Industry manufacturers are required by the Sunshine Act to disclose payments to physicians. These data recently became publicly available, but some manufacturers prereleased their data since 2009. We tested the hypotheses that there would be discrepancies […]

Read more

True, True, Related? Autoimmune Polyglandular Syndrome Type II

Abnormalities in iron metabolism clouded the final diagnosis in a patient with autoimmune polyglandular syndrome. A 20-year-old man presented with a 1-week history of fatigue, sore throat, vomiting, and constipation. He also reported subacute constitutional weakness and darkening of the palmar creases and the nape of his neck in the 9 months prior to presentation. […]

Read more

Reflections on the Physicians Payment Sunshine Act

Society has clearly benefited from the partnership between the pharmaceutical and medical device industries. For more than 100 years there has been an unwritten understanding that industry, working in a market economy, would develop those treatments that physicians and their patients require, while the government would supervise the approval process, as well as regulate the […]

Read more

Medical Complications of Anorexia Nervosa and Bulimia

Anorexia nervosa and bulimia nervosa are serious psychiatric illnesses related to disordered eating and distorted body images. They both have significant medical complications associated with the weight loss and malnutrition of anorexia nervosa, as well as from the purging behaviors that characterize bulimia nervosa. No body system is spared from the adverse sequelae of these […]

Read more