‘Real-World’ Antithrombotic Treatment in AF

‘Real-World’ Antithrombotic Treatment in Atrial Fibrillation: The EORP-AF Pilot Survey   Background Current guidelines strongly recommend that oral anticoagulation should be offered to patients with atrial fibrillation and ≥1 stroke risk factors. The guidelines also recommend that oral anticoagulation still should be used in the presence of stroke risk factors irrespective of rate or rhythm […]

Read more
Joseph S. Alpert, MD

New Critical Review: Decreased Risk for Heart Disease (video)

Primary and secondary prevention has decreased the incidence of acute myocardial infarction and sudden cardiac deaths from the mid- 1960s to the present. Check out this article in the September 2014 issue of The American Journal of Medicine.

Read more

Fatality Risks on the Road and in Space

On February 1, 2013, millions of Americans commemorated the 10-year anniversary of the loss of Space Shuttle Columbia and its 7-member crew. Much less visible, however, was the 10-year anniversary of the 122 automobile crash deaths that also occurred in the United States on February 1, 2003.1 Space travel and road travel do not pose competing risks and […]

Read more

Venous Gangrene

Venous Gangrene and Intravascular Coagulation and Fibrinolysis in a Patient Treated with Rivaroxaban A 67-year-old woman presented with new bilateral leg swelling and was diagnosed with bilateral deep vein thromboses. Rivaroxaban was started at 15 mg twice daily. Ten days later, the patient experienced increased right foot swelling, pain, and cyanosis (Figure). On admission, a right […]

Read more

The Consumption Gene

After years of pondering the over-testing, over-imaging, over-diagnosis, and over-treatment that typify US medicine, I have concluded that, like everything else, it must be genetic: We have evolved a gene that controls (or rather, disinhibits) consumption in all its forms. Although the gene has yet to be identified, I think it should be designated as […]

Read more
Management of Hyponatremia

CME: Management of Patients with Hyponatremia

The American Journal of Medicine is offering a new continuing medical education course entitled: Advances in the Management of Patients with Hyponatremia. Program Overview This continuing medical education activity represents a comprehensive summary of the diagnosis and treatment of all types of hyponatremia. The expert faculty present specific treatment recommendations according to the extracellular fluid […]

Read more
American Journal of Medicine Editor Joseph Alpert

To Dig or Not to Dig

One of my colleagues here in Tucson thinks that digitalis therapy should be relegated to the medical trash heap alongside calomel, bleeding, and purging. I disagree, although digitalis therapy is certainly not as au courant today as it was when I was in training decades ago. Indeed, at that time, various forms of digitalis therapy […]

Read more
tape measure

CME: Advances in the Management of Obesity

The American Journal of Medicine is offering a new continuing medical education course: Advances in the Management of Patients with Obesity. The course is based upon highlights from the 2013 Obesity Society Annual Meeting. Program Overview ObesityWeek 2013 was held on November 11–16, in Atlanta, GA and presented important data for the successful management of […]

Read more
Cardiac Stress Testing

CME: Pharmacological Cardiac Stress Testing

The American Journal of Medicine and The American Journal of Cardiology are offering a new online continuing medical education (CME) course: Update on Pharmalogical Cardiac Stress Testing: Efficacy, Risk Stratification, and Patient Selection. Program Overview Given the rapidly evolving field of cardiac stress testing with respect to new risk stratification algorithms, new agents, and new […]

Read more
Joseph S. Alpert, MD

New Research: Stroke Rates Fall by 40% (video)

Incident strokes in the Medicare population fell by nearly 40% over the last 2 decades, a greater-than-expected decline. Check out Trends in Stroke Rates, Risk, and Outcomes in the United States, 1988 to 2008 the July 2014 issue of The American Journal of Medicine to learn more.

Read more

Cardiac Rehabilitation, Readmissions, and Death After Acute MI

Participation in Cardiac Rehabilitation, Readmissions, and Death After Acute Myocardial Infarction Participation in cardiac rehabilitation has been shown to decrease mortality after acute myocardial infarction, but its impact on readmissions requires examination. Methods We conducted a population-based surveillance study of residents discharged from the hospital after their first-ever myocardial infarction in Olmsted County, Minnesota, from […]

Read more

Muscle Mass Index As a Predictor of Longevity

Muscle Mass Index As a Predictor of Longevity in Older Adults   Obesity, as measured by body mass index (BMI), has not been associated consistently with higher mortality in older adults. This study reveals that muscle mass may be a better predictor of longevity than BMI. Objective Obesity (as defined by body mass index) has […]

Read more