Trends in Stroke Rates, Risk, and Outcomes

Trends in Stroke Rates, Risk, and Outcomes in the United States, 1988 to 2008 Background Stroke is a major cause of morbidity and mortality. We describe trends in the incidence, outcomes, and risk factors for stroke in the US Medicare population from 1988 to 2008. Methods We analyzed data from a 20% sample of hospitalized Medicare […]

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Predictive Parameters of Accelerated Muscle Loss in Men—MINOS Study

Background Aging-related muscle loss is a public health problem. We investigated the association of lifestyle and hormonal factors with a prospectively assessed muscle loss in older men. Methods Among 608 home-dwelling men, aged 60-85 (mean 68) years, lifestyle and health status were evaluated through a questionnaire. Appendicular skeletal muscle mass was estimated using dual-energy x-ray […]

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The Onion

AJM ‘Research’ Featured in The Onion

Is imitation the sincerest form of flattery? If so, The Onion paid a compliment to The American Journal of Medicine in August. A satirical Onion post cites a fictitious research study warning people not to spend too much time together. From The Onion… A study published Thursday in The American Journal Of Medicine determined that it is highly detrimental […]

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Drug-induced Dilemma

Drug-induced Dilemma: Angiokeratomas and Decreased Renal Function   Timing is everything, according to the well-worn aphorism. Yet, it certainly proved true when a diagnosis was sought for a puzzling set of signs and symptoms. An 84-year-old woman was referred to our hospital in December 2012, due to the sudden appearance of multiple eruptive hemorrhagic papules […]

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Cardiac Rehabilitation, Readmissions, and Death After Acute MI

Background Participation in cardiac rehabilitation has been shown to decrease mortality after acute myocardial infarction, but its impact on readmissions requires examination. Methods We conducted a population-based surveillance study of residents discharged from the hospital after their first-ever myocardial infarction in Olmsted County, Minnesota, from January 1, 1987, to September 30, 2010. Patients were followed […]

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‘Real-World’ Antithrombotic Treatment in AF

‘Real-World’ Antithrombotic Treatment in Atrial Fibrillation: The EORP-AF Pilot Survey   Background Current guidelines strongly recommend that oral anticoagulation should be offered to patients with atrial fibrillation and ≥1 stroke risk factors. The guidelines also recommend that oral anticoagulation still should be used in the presence of stroke risk factors irrespective of rate or rhythm […]

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Joseph S. Alpert, MD

New Critical Review: Decreased Risk for Heart Disease (video)

Primary and secondary prevention has decreased the incidence of acute myocardial infarction and sudden cardiac deaths from the mid- 1960s to the present. Check out this article in the September 2014 issue of The American Journal of Medicine.

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Fatality Risks on the Road and in Space

On February 1, 2013, millions of Americans commemorated the 10-year anniversary of the loss of Space Shuttle Columbia and its 7-member crew. Much less visible, however, was the 10-year anniversary of the 122 automobile crash deaths that also occurred in the United States on February 1, 2003.1 Space travel and road travel do not pose competing risks and […]

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Venous Gangrene

Venous Gangrene and Intravascular Coagulation and Fibrinolysis in a Patient Treated with Rivaroxaban A 67-year-old woman presented with new bilateral leg swelling and was diagnosed with bilateral deep vein thromboses. Rivaroxaban was started at 15 mg twice daily. Ten days later, the patient experienced increased right foot swelling, pain, and cyanosis (Figure). On admission, a right […]

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The Consumption Gene

After years of pondering the over-testing, over-imaging, over-diagnosis, and over-treatment that typify US medicine, I have concluded that, like everything else, it must be genetic: We have evolved a gene that controls (or rather, disinhibits) consumption in all its forms. Although the gene has yet to be identified, I think it should be designated as […]

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Management of Hyponatremia

CME: Management of Patients with Hyponatremia

The American Journal of Medicine is offering a new continuing medical education course entitled: Advances in the Management of Patients with Hyponatremia. Program Overview This continuing medical education activity represents a comprehensive summary of the diagnosis and treatment of all types of hyponatremia. The expert faculty present specific treatment recommendations according to the extracellular fluid […]

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American Journal of Medicine Editor Joseph Alpert

To Dig or Not to Dig

One of my colleagues here in Tucson thinks that digitalis therapy should be relegated to the medical trash heap alongside calomel, bleeding, and purging. I disagree, although digitalis therapy is certainly not as au courant today as it was when I was in training decades ago. Indeed, at that time, various forms of digitalis therapy […]

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tape measure

CME: Advances in the Management of Obesity

The American Journal of Medicine is offering a new continuing medical education course: Advances in the Management of Patients with Obesity. The course is based upon highlights from the 2013 Obesity Society Annual Meeting. Program Overview ObesityWeek 2013 was held on November 11–16, in Atlanta, GA and presented important data for the successful management of […]

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Cardiac Stress Testing

CME: Pharmacological Cardiac Stress Testing

The American Journal of Medicine and The American Journal of Cardiology are offering a new online continuing medical education (CME) course: Update on Pharmalogical Cardiac Stress Testing: Efficacy, Risk Stratification, and Patient Selection. Program Overview Given the rapidly evolving field of cardiac stress testing with respect to new risk stratification algorithms, new agents, and new […]

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Joseph S. Alpert, MD

New Research: Stroke Rates Fall by 40% (video)

Incident strokes in the Medicare population fell by nearly 40% over the last 2 decades, a greater-than-expected decline. Check out Trends in Stroke Rates, Risk, and Outcomes in the United States, 1988 to 2008 the July 2014 issue of The American Journal of Medicine to learn more.

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