American Journal of Medicine, internal medicine, medicine, health, healthy lifestyles, cancer, heart disease, drugs

The Impact of Cardiorespiratory Fitness Levels on the Risk of Developing Atherogenic Dyslipidemia

  Low cardiorespiratory fitness has been established as a risk factor for cardiovascular-related morbidity. However, research about the impact of fitness on lipid abnormalities, including atherogenic dyslipidemia, has produced mixed results. The purpose of this investigation is to examine the influence of baseline fitness and changes in fitness on the development of atherogenic dyslipidemia. Methods […]

Read more
close up of a mosquito on skin

The Clinical Spectrum of Zika Virus in Returning Travelers

The clinical spectrum of Zika virus had, to date, been described in small series from endemic/epidemic countries and is not well established. Methods We describe the clinical manifestations of laboratory-proven Zika virus infection in Israeli travelers during December 2015-February 2016, and review all published cases of travel-related Zika virus. Results During the study period, 8 […]

Read more

Renin-Angiotensin System Inhibition and Lower 30-Day All-Cause Readmission in Medicare Beneficiaries with Heart Failure

  Heart failure is the leading cause for 30-day all-cause readmission, the reduction of which is a goal of the Affordable Care Act. There is a growing interest in understanding the impact of evidence-based heart failure therapy on 30-day all-cause readmission. In the current study, we examined the impact of angiotensin-converting enzyme inhibitors or angiotensin […]

Read more

Genetically Informed Medicine

  As many readers will remember from an earlier editorial entitled “What’s in a Word? Using Words Carefully,”1 I pointed out the danger in using words without first carefully considering the implications of the written or spoken terms for individuals and for society. In this editorial, I described one of my patients who had mistakenly been […]

Read more

How Physicians Can Reduce Suicide—Without Changing Anyone’s Mental Health

Suicide is the leading cause of injury death in the US, and its rate has increased in recent years. On an average day, over 115 Americans take their lives. A typical physician’s patient is more likely to die from suicide than from motor vehicle crashes, falls, unintentional overdose, or homicide. Most people who die by suicide […]

Read more

Emerging Concepts in Glaucoma and Review of the Literature

Glaucoma is the most commonly acquired optic neuropathy. It represents a public health challenge because it causes an irreversible blindness. Emerging evidence indicates that the pathogenesis of glaucoma depends on several interacting pathogenetic mechanisms, which include mechanical effects by an increased intraocular pressure, decreased neutrophine-supply, hypoxia, excitotoxicity, oxidative stress, and the involvement of autoimmune processes. […]

Read more

Eyelid Metastasis in Non-Small Cell Lung Cancer: Diagnosis and Management

A 75-year-old man presented with a left lower eyelid lesion that had progressively enlarged over 2 months without bleeding, irritation, or change in vision. Shortly after noticing the eyelid lesion, he also noted hoarseness of his voice and enlarged lymph nodes in the left side of his neck. His review of systems was otherwise negative […]

Read more

A Picture’s Worth: Giant Cell Arteritis

The ubiquitous smartphone became a helpful diagnostic tool when a patient used one to snap a photograph of her tongue. Although her symptoms were vague and nonspecific, her photograph facilitated the diagnosis of a serious, potentially debilitating illness. A generally healthy 63-year-old woman presented with a 1-week history of sore throat and periodic burning tongue […]

Read more

Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and Majocchi’s Granuloma

A 27-year-old woman presented for a second opinion with chest pain, dyspnea, and a worsening rash with new pustules. Three weeks before presentation she developed a small rash on her anterior right lower abdomen. After treatment with topical hydrocortisone and mupirocin, oral valganciclovir and clindamycin, the rash increased in size, developed central clearance, and became warm […]

Read more